Medicamentos para otitis media aguda
Estos son los medicamentos que KitCal reúne para otitis media aguda. La elección depende de la edad, la gravedad, el germen o la causa, y de las guías locales.
Código CIE-10 de referencia: H66.9.
Dosis de cada medicamento
Dosis por kilo de peso tal como figuran en KitCal. En la app se ingresa el peso y se obtiene la dosis en mg y el volumen a administrar.
Ácido Clavulánico - Amoxicilina
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Jarabe Oral 125mg/5cc · 250mg/5cc · 400mg/5cc | 30-50mg/kg x día | cada 8 horas | 2400mg |
| Tableta Oral 500mg · 800mg | 30-50mg/kg x día | cada 8 horas | 2400mg |
Una vez preparada; conservar la suspensión entre 4-8°C; la suspensión con 400mg/5cc se administra cada 12 horas.
Amoxicilina
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Jarabe Oral 125mg/5cc · 250mg/5cc · 500mg/5cc | Infecciones Comunes30 - 50 mg/kg x día | cada 8 horas | 2625mg |
| Otitis Media Aguda80 mg/kg x día | cada 12 horas | 2625mg | |
| Tableta Oral 250mg · 500mg · 875mg | Infecciones Comunes30 - 50 mg/kg x día | cada 8 horas | 2625mg |
| Otitis Media Aguda80 mg/kg x día | cada 12 horas | 2625mg |
Azitromicina
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Jarabe Oral 200mg/5cc | 10 mg/kg x día | cada 24 horas (durante 3 días) | 500mg |
| Tableta Oral 500mg | 10 mg/kg x día | cada 24 horas (durante 3 días) | 500mg |
No administrar en insuficiencia hepática
Cefaclor
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Jarabe Oral 250mg/5cc · 375mg/5cc | 250mg40 mg/kg x día | cada 8 horas | 1000 mg |
| 375mg40 mg/kg x día | cada 12 horas | 1000 mg | |
| Cápsula Oral 250mg · 500mg | 40 mg/kg x día | cada 8 horas | 1000 mg |
Dosis máxima: 1g/día
Ceftriaxona
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Vial Endovenosa; Intramuscular 250mg · 500mg · 1000mg · 2000mg | Por defecto20 - 80 mg/kg x día | cada 12 - 24 horas | — |
| Meningitis100 mg/kg x día | cada 12 horas | — | |
| Otitis media aguda50 mg/kg x dosis | — | — |
Cefuroxima
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Jarabe Oral 250mg/5cc | 15 - 20 mg/kg x día | cada 12 horas | 1000 mg |
| Tableta Oral 250mg · 500mg | 15 - 20 mg/kg x día | cada 12 horas | 1000 mg |
| Vial Endovenosa; Intramuscular 750mg · 1500mg | 50 - 150 mg/kg x día | cada 8 horas | 1000 mg |
Ofloxacino
| Presentación | Dosis | Frecuencia | Dosis máxima |
|---|---|---|---|
| Gotas Ótica 0.3% | 5 gotas en el oído cada 12 horas | — | — |
Fuentes
Ver las 57 referencias de estos medicamentos
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- Giuliano C, Patel CR, Kale-Pradhan PB. A Guide to Bacterial Culture Identification And Results Interpretation. P T. 2019 Apr;44(4):192-200. PMID: 30930604; PMCID: PMC6428495.
- Fosberg K, Ankerman K, Black D, Boudreau D, Brummel G, Cooper W, et al. Azithromycin and Levofloxacin Use and Increased Risk of Cardiac Arrhythmia and Death. Ann Fam Med. 2014 Mar-Apr;12(2):121-7. doi: 10.1370/afm.1591. PMID: 24615305; PMCID: PMC3948763.
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- World Health Organization (WHO). The selection and use of essential medicines 2023: Executive summary of the report of the 24th WHO Expert Committee on the selection and use of essential medicines. 2023 Oct 16 [Internet]. Geneva: WHO; 2023 [citado 2024]. Disponible en: https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2023.02
- Trac MH, McArthur E, Jandoc R, Dixon SN, Nash DM, Hackam DG, et al. Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. CMAJ. 2016 Apr 5;188(7):E120-E129. doi: 10.1503/cmaj.150901. PMID: 26903359; PMCID: PMC4823801.
- electronic Medicines Compendium (eMC). Cefaclor 500mg capsules (Distaclor): Summary of Product Characteristics. London: eMC; 2025 Dec 8 [consultado 2026 Feb 17]. Disponible en: https://www.medicines.org.uk/emc/product/15784/smpc
- National Institutes of Health (NIH) / DailyMed. Cefaclor Capsules USP: Prescribing Information. Bethesda (MD): National Library of Medicine; 2025 Apr 30 [consultado 2026 Feb 17]. Disponible en: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=2f61354e-bcb0-41aa-955f-51eabc11387b
- Drugs.com. Cefaclor: Package Insert / Prescribing Information. Auckland: Drugs.com; 2025 Nov 3 [consultado 2026 Feb 17]. Disponible en: https://www.drugs.com/pro/cefaclor.html
- Birmingham and Solihull Integrated Medicines Optimisation Committee (IMOC). Cefaclor: Formulary status. En: Birmingham and Surrounds Formulary. Birmingham (UK): NHS; 2025 [consultado 2026 Feb 17]. Disponible en: https://www.birminghamandsurroundsformulary.nhs.uk/chaptersSubDetails.asp?FormularySectionID=5&SubSectionRef=05.01.02.01&SubSectionID=A100&drugmatch=1682
- Drugs.com. Cefaclor Dosage Guide + Max Dose, Adjustments. Auckland: Drugs.com; 2025 Jun 25 [consultado 2026 Feb 17]. Disponible en: https://www.drugs.com/dosage/cefaclor.html
- American Society of Health-System Pharmacists (ASHP). Cefaclor Monograph for Professionals. En: AHFS DI Essentials. Bethesda (MD): ASHP; 2025 Sep 29 [consultado 2026 Feb 17]. Disponible en: https://www.drugs.com/monograph/cefaclor.html
- Pediatric Oncall. Cefaclor: Drug Index. Mumbai: Pediatric Oncall; 2025 Oct 9 [consultado 2026 Feb 17]. Disponible en: https://www.pediatriconcall.com/drugs/cefaclor/374
- Cefaclor in Dentistry: Uses, Benefits & Guidelines. ENT Head and Neck Pharma Guide; 2025 Sep 24 [consultado 2026 Feb 17]. Disponible en: https://ceorlhns2017.com/cefaclor-in-dentistry-uses-benefits-guidelines
- World Health Organization. Web Annex A: Evidence-to-decision framework and systematic review to update the WHO treatment recommendations for Neisseria gonorrhoeae. En: Updated recommendations for the treatment of Neisseria gonorrhoeae, Chlamydia trachomatis and Treponema pallidum (syphilis), and new recommendations on syphilis testing and partner services [Internet]. Geneva: World Health Organization; 2024 [consultado 17 Feb 2026]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK605892/
- Brust-Sisti L, Sturgill M, Cohen J, Monil T, Suda KJ, Raman V, et al. Comparative Efficacy of High- and Low-Dose Ceftriaxone Regimens: A Systematic Review and Meta-Analysis. Ann Pharmacother. 2025 Jul 27:10600280251346777. doi: 10.1177/10600280251346777. Epub ahead of print. PMID: 40876848.
- Miari VF, Messina Mosoff J, Chico RM. Minimum Inhibitory Concentrations of Extended-Spectrum Cephalosporins: A Systematic Review and Meta-Analysis of Neisseria gonorrhoeae Treatment Failures. Sex Transm Dis. 2025 May;52(5):279-284. doi: 10.1097/OLQ.0000000000002116.
- Hu C, Li G, Chen D, Li Y, Tan Z, Gao F. Antibiotic for community-acquired pneumonia in hospitalized adults: A systematic review and Bayesian network meta-analysis. Respir Med. 2025 Aug;244:108168. doi: 10.1016/j.rmed.2025.108168. Epub 2025 Jun 18. PMID: 39516189
- Somakumar S, Anbu Raj SE, Rodrigues GS, Rajesh V. Clinical Efficacy and Safety of Ceftriaxone in Surgical Prophylaxis: A Systematic Review and Meta-Analysis. Indian J Pharm Educ Res. 2024 Apr 1;58(2):s332-s339.
- Tsai D, Zam BB, Tongs C, Chiong F, Sajiv C, Pawar B, et al. Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients-a population pharmacokinetic study. J Antimicrob Chemother. 2023 Aug 1;78(8):2024-2032. doi: 10.1093/jac/dkad202. PMID: 37367723.
- Ceftriaxone [Internet]. PharmaKB; [consultado 17 Feb 2026]. Disponible en: https://app.pharmakb.com/drugs/Ceftriaxone
- Agencia Española de Medicamentos y Productos Sanitarios. Ficha técnica Cefuroxima Sandoz 500 mg comprimidos recubiertos EFG [Internet]. Madrid: AEMPS; 2022 [consultado 17 Feb 2026]. Disponible en: https://cima.aemps.es/cima/dochtml/ft/71020/FichaTecnica_71020.html
- Agencia Española de Medicamentos y Productos Sanitarios. Ficha técnica Cefuroxima Normon 250 mg y 500 mg comprimidos recubiertos con película EFG [Internet]. Madrid: AEMPS; 2021 [consultado 17 Feb 2026]. Disponible en: https://cima.aemps.es/cima/dochtml/ft/68115/FichaTecnica_68115.html
- Universidad Nacional Autónoma de México - Facultad de Medicina. Cefuroxima: suspensión y solución inyectables [Internet]. México DF: UNAM; [revisado 2023] [consultado 17 Feb 2026]. Disponible en: https://www.facmed.unam.mx/bmd/gi_2k8/prods/PRODS/Cefuroxima.htm
- Rodríguez-Gascón A, Aguirre-Quiñonero A, Canut-Blasco A. Are oral cefuroxime axetil, cefixime and cefditoren pivoxil adequate to treat uncomplicated acute pyelonephritis after switching from intravenous therapy? A pharmacokinetic/pharmacodynamic perspective. Enferm Infecc Microbiol Clin (Engl Ed). 2020 Aug-Sep;38(7):306-311. doi: 10.1016/j.eimc.2020.01.007. Epub 2020 Feb 27. PMID: 32115200.
- Suárez FSR, Arias YL, Leyva YR. Efectividad y costos de la cefuroxima intracameral en la profilaxis de la endoftalmitis poscirugía de catarata. Rev Mex Oftalmol. 2017 Mar-Abr;91(2):67-72.
- MedlinePlus. Cefuroxima [Internet]. Bethesda (MD): National Library of Medicine (EE.UU.); [revisado 2023 Jun 15; consultado 17 Feb 2026]. Disponible en: https://medlineplus.gov/spanish/druginfo/meds/a601206-es.html
- Vidal Vademecum Spain. Cefuroxima (J01DC02) [Internet]. Madrid: Vidal Group; [actualizado 2018 Mar 8; consultado 17 Feb 2026]. Disponible en: https://www.vademecum.es/principios-activos-cefuroxima-j01dc02-es
- U.S. Food and Drug Administration (FDA). FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions [Internet]. Silver Spring (MD): FDA; 2018 Jul 10 [actualizado 2023 Dic 12; citado 15 Feb 2026]. Disponible en: https://www.fda.gov ews-events/press-announcements/fda-updates-warnings-fluoroquinolone-antibiotics-risks-mental-health-and-low-blood-sugar-adverse
- European Medicines Agency (EMA). Disabling and potentially permanent side effects lead to suspension or restrictions of quinolone and fluoroquinolone antibiotics [Internet]. Amsterdam: EMA; 2019 Feb 11 [citado 15 Feb 2026]. Disponible en: https://www.ema.europa.eu/en ews/disabling-potentially-permanent-side-effects-lead-suspension-or-restrictions-quinolone-fluoroquinolone-antibiotics
- Agencia Española de Medicamentos y Productos Sanitarios (AEMPS). Fluoroquinolonas de administración sistémica: nuevas restricciones de uso [Internet]. Madrid: AEMPS; 2019 Abr [citado 15 Feb 2026]. Disponible en: https://www.aemps.gob.es/informa otasinformativas/medicamentosusohumano-3/seguridad-1/2019-seguridad-1/fluoroquinolonas-de-administracion-sistemica-nuevas-restricciones-de-uso/
- Drugs.com. Ofloxacin (en español) [Internet]. Last updated 14 Feb 2024 [citado 15 Feb 2026]. Disponible en: https://www.drugs.com/mtm_esp/ofloxacin.html
- Memorial Sloan Kettering Cancer Center. Ofloxacin (Systemic) [Internet]. New York: MSKCC; [citado 15 Feb 2026]. Disponible en: https://www.mskcc.org/es/cancer-care/patient-education/medications/pediatric/ofloxacin-systemic
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Preguntas frecuentes
¿Qué medicamentos se usan para otitis media aguda?
KitCal reúne 7 medicamentos para otitis media aguda: Ácido Clavulánico - Amoxicilina, Amoxicilina, Azitromicina, Cefaclor, Ceftriaxona, Cefuroxima y Ofloxacino. La elección depende de la edad, la gravedad y las guías locales.
¿Cuál es la dosis de ácido clavulánico - amoxicilina para otitis media aguda?
Ácido Clavulánico - Amoxicilina (Jarabe): 30-50mg/kg x día, cada 8 horas. Dosis máxima: 2400mg. Con el peso del paciente, KitCal calcula la dosis y el volumen exactos.
¿Cómo se calcula la dosis por peso?
Se multiplica la dosis por kilo por el peso del paciente y se divide según la frecuencia indicada, sin superar la dosis máxima. Después se convierte a volumen según la concentración de la presentación. La app de KitCal hace este cálculo automáticamente.
¿Cuál es el código CIE-10 de otitis media aguda?
El código CIE-10 de referencia es H66.9.
Otras patologías
Contenido referencial para profesionales de la salud. No reemplaza el juicio clínico ni la evaluación del paciente.